Sexual Medicine Research Team
Our Works in Progress
The multidisciplinary nature of our focused Gender and Sexuality Research Center has been the major strength of our research since we began our work in 2010. SMRT has a variety of ongoing projects ranging from specialties such as Urology, OB/GYN, psychiatry and everything in between! Here are our current projects that are in progress for presentation and journal submission.
Accessibility of Hormone Therapies Amongst ISSWSH Providers by Region
Contact: Dr. Alyssa Yee, Olivia Paulsen
This survey explores the regional availability and accessibility of hormone therapies provided by ISSWSH members, identifying potential barriers to treatment across different geographic areas.
Age- and Race-Related Differences in Clitoral Anatomy Across the Adult Lifespan
Contact: Shaniel Bowen
This retrospective study investigates age and racial differences in anatomical features of the clitoris, such as size, position, and shape, among adult women. It also examines how demographic and medical history factors correlate with these anatomical features.
Analysis of Orgasm Assessments (Provider and Patient Perspectives)
Contact: Eliza Burr
This project surveys sexual health providers and patients to evaluate if existing validated assessments of orgasm accurately reflect the orgasmic experiences reported. Currently, a revised literature review is in progress.
A Patient-Driven Redefinition of the Symptomatology of Post-Orgasmic Illness Syndrome
Contact: Isaac Bronson
This project aims to revisit the criteria and symptom clusters for Post-Orgasmic Illness Syndrome (POIS) originally defined by Waldinger et al. in 2002. Using a retrospective qualitative analysis of patient-administered polls, the study will design a cross-sectional survey to refine and expand our understanding of POIS symptomatology.
Assessment of Resident Education in the Diagnosis and Treatment of Common Conditions of Female Sexual Dysfunction
Contact: Mariah Milazzo, Abby Kohut-Jackson, Olivia Nigris
Surveys are being used to evaluate residents' knowledge and treatment of common female sexual dysfunction conditions, such as hypoactive sexual desire disorder and female orgasmic disorder, to identify gaps in medical education and practice.
B12 and Sexual Function
Contact: Eliza Burr
This project investigates the relationship between B12 deficiency and sexual function, exploring potential neurological and physiological impacts on sexual health
Bladder Cancer Masked by PGAD/PGID
Contact: Eveline Poirier, Sarah Ponce, Melissa Avdeeff
This case report focuses on a patient with Persistent Genital Arousal Disorder (PGAD), where symptoms masked an underlying bladder cancer. The study emphasizes the need for thorough diagnostic evaluations in patients with complex sexual health symptoms.
Clitoral Size, Position, and Shape are Associated with Sexual Function Following Vaginal Surgery
Contact: Shaniel Bowen
This cross-sectional ancillary study explores the relationship between anatomical features of the clitoris and postoperative sexual function in women who have undergone vaginal surgery. It aims to identify key factors that impact sexual activity status and outcomes.
Clitoral Ultrasound Studies
Contact: Olivia Paulsen & Dr. Kim Lovie Murdaugh
This feasibility study uses clitoral ultrasound to assess vascularity and explore its potential link to atherosclerotic risk factors and sexual dysfunction. The study is currently in the drafting stage.
Evaluating Sexual Health Curricula at Medical Schools in the Northeast
Contact: Mariah Milazzo
This project involves a rubric-based review of sexual health curriculum materials at medical schools in the Northeast. The team is currently progressing on manuscript preparation.
Genitourinary Syndrome of Lactation
Contact: Sara Perelmuter
This ongoing project focuses on the hormonal changes during lactation and postpartum, particularly hypoestrogenism, and their effects on vulvovaginal health. Many postpartum women experience a range of genitourinary symptoms, often underrecognized, that significantly impact their quality of life. To address this, we have proposed the term “Genitourinary Syndrome of Lactation” (GSL) to describe these symptoms, which include vaginal dryness, dyspareunia, urinary issues, and changes in sexual function. Our team has published a literature review and is currently conducting a systematic review and survey to better understand GSL, its prevalence, and the challenges in treating affected women. Visit our page to learn more about GSL!
GSM Terminology Reform Task Force
Contact: Aimee Clouder
This advocacy project focuses on reforming the terminology used to describe Genitourinary Syndrome of Menopause (GSM) to better reflect patient experiences and improve clinical communication.
How Are People with Various Female Sexual Dysfunction Conditions Described on Reddit Communities?
Contact: Ifeoma Ikedionwu
This content analysis study examines how individuals with female sexual dysfunction are portrayed on Reddit, identifying common themes and narratives to understand the social context of these conditions.
Labia Minora Review Paper
Contact: Adedayo Adetunji
This review focuses on the anatomy, evolution, and pathophysiology of the labia minora, seeking to consolidate current knowledge. A manuscript is in progress following a presentation at ISSWSH 2024.
Labia Minora Systematic Review
Contact: Sara Perelmuter
This systematic review aims to characterize the anatomy, histology, innervation, and vasculature of the labia minora. The review seeks to provide a comprehensive understanding of the labia minora's structure and function.
LET'S [assess how 4th year medical students] TALK ABOUT SEX!
Contact: Angie Murthy
This needs assessment project surveys medical students who have completed their core rotations to understand their experiences discussing sexual health with patients. The project is currently expanding to include a nationwide survey, with plans for manuscript development.
Life as a Patient-Doctor
Contact: Stephanie Moss, MD
This podcast and interview series explores the lived experiences of individuals who navigate the healthcare system both as patients and healthcare professionals. The series is available on YouTube, Apple, and Spotify, with transcripts and additional resources provided online.
Lumbosacral Disc Disease and Delayed Orgasm
Contact: Abby Kohut-Jackson
This review explores the relationship between lumbosacral disc disease and delayed ejaculation, focusing on sensory nerve pathways and their impact on sexual function. The draft is being finalized.
Pelvic and Vulvovaginal Pain in Hispanic Women
Contact: Sarah Ponce, Yahiri Santiago-Lastra
This systematic review addresses the prevalence and management of pelvic and vulvovaginal pain among Hispanic women, highlighting disparities in healthcare access and outcomes.
Pelvic and Vulvovaginal Pain in Medical Trainees
Contact: Sarah Ponce, Emily Markarian, Dr. Ferzandi, Dr. Rubin
This cross-sectional survey aims to understand the prevalence and underlying causes of pelvic and vulvovaginal pain among medical trainees, highlighting gaps in diagnosis and care.
PGAD/Mounjaro (Tirzepatide Injection)
Contact: Eveline Poirier, Maya Roytman, Mariah MacKinnon Millazzo
This case report investigates a patient who experienced complete resolution of PGAD symptoms after starting Mounjaro (Tirzepatide injection). The project includes plans to interview the patient and finalize IRB approval for further studies.
Post-orgasmic Illness Syndrome (POIS) Registry
Contact: Olivia Paulsen
This registry aims to collect data on POIS, a poorly understood condition that primarily affects people with penises and has an immunologic component. The project is currently navigating IRB issues.
Qualitative Analysis of Online Discussion About GLP1/GIP Medications and Sexual Side Effects
Contact: Eveline Poirier, Eliza Burr, Geviana Partington
This qualitative study analyzes online discussions to assess awareness and experiences related to sexual side effects of GLP1/GIP medications. It aims to fill gaps in patient education and physician communication.
Representation of Sexual Dysfunction in Commonly Used USMLE Step Exam-Specific Third-Party Resources
Contact: Emilyann Key
This needs assessment study evaluates how frequently sexual dysfunctions are represented in USMLE step exam-specific third-party resources. It aims to identify whether these dysfunctions are presented in terms of dysfunction versus healthy sexual function and to what extent they are discussed comprehensively.
Review Paper: Isotretinoin and Vulvovaginal Symptoms
Contact: Sri Contractor
This literature review examines the potential link between isotretinoin, commonly used to treat acne, and vulvovaginal symptoms, particularly dryness and irritation.
Sexual Function/Orgasm in Pregnancy
Contact: Jackline Lasola, Mariah Milazzo
This literature review aims to synthesize the current state of knowledge on sexual function and orgasm during pregnancy, identifying gaps and areas for future research.
Shockwave Therapy for Stress Urinary Incontinence
Contact: Abby Kohut-Jackson
This pilot study investigates the efficacy of shockwave therapy for treating stress urinary incontinence. Data collection is ongoing, and initial findings have been presented at ISSWSH 2024.
Systematic Review: Prevalence of Vulvodynia in Hispanic Women
Contact: Sarah Ponce, Yahir Santiago-Lastra
This systematic review explores the prevalence of vulvodynia in Hispanic women and discusses the need for culturally competent treatment approaches that address socioeconomic barriers to care.
The Impact of Fertility Treatment (IVF) on Sexual Function
Contact: Kalyani Parwatkar
This cross-sectional ancillary study investigates how fertility treatments, particularly IVF, impact female sexual function. By monitoring symptoms throughout the IVF process, the study aims to draw connections between hormonal treatments and changes in sexual function.
The Psychosocial Burden of Post-Orgasmic Illness Syndrome
Contact: Isaac Bronson
This cross-sectional mixed-methods study focuses on the psychosocial burden experienced by individuals with Post-Orgasmic Illness Syndrome (POIS). The study includes focus groups to explore the emotional and social challenges associated with this condition.
The Use of In-Office Nitrous Oxide for Vulvodynia
Contact: Prianka Kumar & Olivia Paulsen
This case-control study explores whether nitrous oxide can alleviate discomfort during pelvic exams for patients with vulvodynia and help differentiate etiologies. The project is funded and IRB-approved, with data collection underway.
Using Clitoral Ultrasound to Look at CAD Risk Factors, Hypoestrogenism, and Sexual Dysfunction
Contact: Sarah Ponce, Eliza Burr
This case-control study examines clitoral pulse amplitude as potentially correlated with atherosclerotic risk factors. While links to sexual dysfunction have been studied previously, this project represents the first detailed assessment of sexual dysfunction.
